Kangaskhan is a Generation I Pokémon that is known for its powerful physical attacks and high hit points. It is a Normal-type Pokémon and is the only Pokémon that destylers can evolve from a baby Pokémon. Kangaskhan has a unique feature where it has a pouch that can carry its child, known as a "Kangaskhanite."

When it comes to determining the best nature for Kangaskhan, there are a few options that stand out as the most beneficial. These include:

  1. Jolly Nature: This nature increases Kangaskhan's Speed stat while decreasing its Special Attack stat. This can be useful for Kangaskhan as it is a physically-oriented Pokémon and would benefit more from increased Speed than Special Attack. Jolly nature also allows Kangaskhan to outspeed and KO some of the fastest threats in the metagame such as Talonflame, Greninja and Infernape.

  2. Adamant Nature: This nature increases Kangaskhan's Attack stat while decreasing its Special Attack stat. This can be useful for Kangaskhan as it is a physically-oriented Pokémon and would benefit more from increased Attack than Special Attack. This nature allows Kangaskhan to hit harder, and also be more consistent in its damage output.

  3. Careful Nature: This nature increases Kangaskhan's Special Defense stat while decreasing its Special Attack stat. This can be useful for Kangaskhan as it is a physically-oriented Pokémon and would benefit more from increased Special Defense than Special Attack. This nature allows Kangaskhan to take special hits better, and also avoid getting OHKO by some special move such as Thunder, Ice Beam, etc.

Other natures such as Impish and Brave also have their merits, but the above natures are generally considered to be the most beneficial for Kangaskhan.

When it comes to moveset, Kangaskhan has a diverse movepool with powerful moves such as Return, Sucker Punch, and Power-Up Punch. Return is Kangaskhan's most powerful STAB move and it has 100 base power, Sucker Punch is a priority move that allows Kangaskhan to outspeed and KO some of the fastest threats in the metagame, and Power-Up Punch is a move that allows Kangaskhan to boost its attack and speed, but it has a drawback of lowering the accuracy.

Kangaskhan can also use moves such as Earthquake and Stone Edge to hit other Pokémon super effectively, while it can also use moves like Substitute, Focus Punch, and Thunder Wave to support its team.

In conclusion, Kangaskhan is a powerful and versatile Pokémon that can be used in a variety of ways. Jolly nature is considered the best nature for Kangaskhan as it increases its Speed and allows it to outspeed and KO some of the fastest threats in the metagame. The use of Return, Sucker Punch and Power-Up Punch as its main moves, and the support moves such as Earthquake and Stone Edge, make Kangaskhan a formidable force in battle. Careful nature is also considered as a good option for Kangaskhan to take special hits better and avoid getting OHKO by some special move.